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Dianabol Cycle Pharma TRT

Dianabol (Methandrostenolone)

A synthetic anabolic–androgenic steroid first developed in the 1950s, Dianabol has been widely studied for its effects on muscle growth and performance enhancement. Its popularity stems from its potent ability to increase protein synthesis and nitrogen retention in skeletal muscle, thereby promoting anabolism.



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1. What Is Dianabol?




Chemical Identity: Methandrostenolone is a derivative of testosterone that contains a methyl group at the C17α position.


Legal Status: In many jurisdictions it is classified as a controlled substance and requires a prescription for legitimate medical use (e.g., treatment of muscle wasting disorders).


Common Forms: Injectable solutions, oral tablets, or capsules. Oral forms often incorporate a 17α-methyl group to enhance first‑pass metabolism.







2. Pharmacological Effects



System Primary Effect Mechanism


Muscular Increased protein synthesis, hypertrophy Activation of androgen receptors → upregulation of anabolic genes


Endocrine Suppression of gonadotropin release (LH/FSH) Negative feedback on hypothalamic‑pituitary axis


Hepatic Elevated liver enzymes (AST, ALT) 17α‑methylation leads to hepatotoxic metabolites


Cardiovascular Mild elevation in blood pressure Androgen receptor activation in vascular smooth muscle


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3. Common Side Effects




Gastrointestinal: Nausea, abdominal pain, diarrhea


Dermatologic: Acne vulgaris, oily skin, hair growth (hirsutism)


Neurologic: Headache, dizziness


Hepatic: Elevated liver enzymes; in rare cases, fulminant hepatic failure


Metabolic: Weight gain, fluid retention







4. Rare or Serious Adverse Events



Event Incidence (approx.) Clinical Notes


Hepatic Failure